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Membrane potential of the thalamocortical cell determines the functional effect of presynaptic bursts in a PGN cell.A, B, Depolarization of the thalamocortical cell by only 3 mV results in abolition of rebound burst firing [−72 mV (A) to −69 mV (B)]. C, Further depolarization of the thalamocortical cell to tonic firing mode reveals that presynaptic bursts in the PGN neuron can inhibit the generation of action potentials.
