Table 2.
Kinetics of normalized GABA-evoked current using fast perfusion (application time, 2 msec)
| Constant | 1 mm GABA | 10 mm GABA | |||
|---|---|---|---|---|---|
| Control | 30 μm CPZ | 100 μm CPZ | Control | 100 μm CPZ | |
| τfast (msec) | 8.7 ± 1.4 | 9.7 ± 1.0 | 6.2 ± 0.5 | 4.9 ± 0.4 | 6.4 ± 0.6 |
| Afast | 0.62 ± 0.02 | 0.65 ± 0.02 | 0.82 ± 0.02* | 0.51 ± 0.02 | 0.85 ± 0.02* |
| τslow (msec) | 123.5 ± 12 | 133 ± 13 | 139 ± 22 | 104 ± 9 | 114 ± 12 |
| Rise time (msec) | 1.12 ± 0.08 | 1.61 ± 0.19* | 1.82 ± 0.06* | 0.76 ± 0.05 | 0.81 ± 0.06 |
Aslow = 1 − Afast. The averages are calculated from at least 10 data values. Asterisk indicates that the values of parameters are significantly different from the control ones (p < 0.05).