Fig. 5.
Ankyrin-3/G distributions in rat optic nerves during development. a, b, A P7 optic nerve shows that ankyrin-3/G (a,arrowheads) is found at the edges of MAG-labeled oligodendrocyte processes (b,arrowheads). c, d, A P9 rat optic nerve double-labeled for ankyrin-3/G (c) and Na+ channels (d) illustrates a site with colocalized immunoreactivity (arrows) and one in which Na+ channel label was absent (arrowhead). e, f, A P14 optic nerve, double-labeled with ankyrin-3/G (e) and Na+ channel (f) antibodies. g, At P13, some nodes had a gap between the intense nodal and weaker paranodal ankyrin-3/G staining (arrowhead). h, In adults, small-caliber axons (arrow) had prominent paranodal ankyrin-3/G, but larger axons did not (arrowhead). Scale bars, 10 μm.