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Variable effects of NE on single N-channels. Prepulse and postpulse pseudomacroscopic currents were measured as the average between 5 and 15 msec into the 40 msec depolarization to +30 mV. The ratio of postpulse current to prepulse current was calculated for six control patches and 18 patches exposed to 100 μmNE. A ratio of ∼1 indicates no modulation, whereas ratios > 1 are positively correlated with the magnitude of inhibition.
