Fig. 2.
Pattern of food intake and body weight gain after disruption of ARC/PVN connections. Left, Lesioned rats (n = 16) ate more food than sham rats (n = 15) in dark and in light.Middle, Body weight gain was greater in lesioned rats as compared with shams. The increased weight of lesioned rats as compared with shams is attributable to less weight loss during the light period. The difference in body weight was significant within 24 hr of surgery.Right, Caloric efficiency was the same in lesioned and sham rats. This indicates that lesioned animals have a nutritional obesity unrelated to a decrease in metabolic rate. *p < 0.05; **p < 0.01.