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Dose–response and temporal profiles of the hippocampus extracellular norepinephrine response to an acute oral administration of methylphenidate (1.0, 2.5, 5.0 mg/kg), presented as absolute values corrected for probe recovery. Values represent the mean ± SEM. BL values are the median of the three samples collected immediately before drug administration. *p < 0.05 compared with the sample collected immediately before drug administration.
