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Expression of IGF-1 in the rat cerebral cortex after prolonged hypoxia. A, Ribonuclease protection assay showing that hypobaric hypoxia (0.5 ATM, equivalent to 10% O2 for 1 hr–7 d) did not affect IGF-1 mRNA levels in the brain cortex compared with normoxic control (C).B, Immunoblot showing no changes in IGF-1 protein levels in the brain cortex during hypobaric hypoxia (1h–7d).
