Table 3.
Odds ratio (OR) estimates for log10(ID50) and covariates based on the model of infection risk conditional on log10(ID50), epitope of the bNAb, challenge virus, and the interaction between log10(ID50) and challenge virus (SF162P3 vs. other). See also Table S3.
| OR | 95% CI | p-value | |
|---|---|---|---|
| log10(ID50) for virus other than SHIVSF162P3 | 0.012 | (0.003,0.054) | <0.001 |
| log10(ID50) for virus SHIVSF162P3 | 0.17 | (0.057,0.51) | 0.002 |
| Epitope relative to MPER | |||
| CD4 Binding Site | 801 | (58, 16243) | <0.001 |
| V1V2 | 1030 | (43, 24887) | < 0.001 |
| V3-glycan | 4120 | (173, 97943) | < 0.001 |
| Virus relative to SHIVBaL/SHIVBaLP4 | |||
| SHIVSF162P4 | 1.98 | (0.29,13.43) | 0.49 |
| SHIV325C | 0.008 | (0,0.18) | 0.002 |
| SHIV327C | 0.83 | (0.18,3.79) | 0.81 |
| SHIVAD8EO | 0.52 | (0.12,2.17) | 0.37 |
| SHIVBG505 | 0.095 | (0.016,0.57) | 0.01 |
| SHIVSF162P3 | 0 | (0,0.016) | <0.001 |