Figure 2. Allelic enrichment in the Finnish population and its effect on genetic discovery.
A) Relationship between MAF and estimated effect size for associations discovered in FinMetSeq. Each variant reaching significance in FinMetSeq is plotted, with associations in Table 1 represented by dark blue points (FinMetSeq MAF) and green points (NFE MAF). Purple lines indicate 80% power curves for sample sizes of 10,000 and 20,000 at α=5x10-7.
B) Same plot as in A, highlighting the variants in Table 1 only reaching significance in the combined analysis.