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. 2006 Mar 8;26(10):2714–2723. doi: 10.1523/JNEUROSCI.2977-05.2006

Table 3.

Parameters of slow inactivation

Channel Voltage dependence of slow inactivation
Entry into slow inactivation at −10 mV
Recovery from slow inactivation
τfast
τslow
n τfast
τslow
n
V1/2 (mV) a(mV) n s % s % s % s %
WT plus β1 −46.2 ± 4.5 5.6 ± 0.8 12 0.79 ± 0.06 73 ± 8 19.6 ± 4.1 27 ± 8 5 0.85 ± 0.03 48 ± 3 40.5 ± 8.2 47 ± 4 6
R859C plus β1 −46.1 ± 3.8 6.4 ± 1.0 13 0.81 ± 0.07 77 ± 10 20.6 ± 1.2 23 ± 10 5 0.63 ± 0.1* 42 ± 4* 141.7 ± 10.2* 57 ± 4* 6
WT plus R859C plus β1 NDa NDa NDa NDa NDa NDa 0.80 ± 0.13 56 ± 2* 59.7 ± 10.7* 39 ± 2* 4

aNot determined because the voltage dependence of slow inactivation and entry into slow inactivation were not affected by the R859C mutation.

The asterisk indicates a statistically significant difference from wild-type (WT) α plus β1 at p < 0.05.