Figure 2.
Ghrelin has an excitatory effect on SFO neurons. A, B, Single-cell recordings showing depolarization and an increase in action potential frequency induced by application of 1 nm ghrelin (black bar) and return to baseline membrane potential and frequency after removal of ghrelin from the bath. C, Mean membrane potential change in ACSF (white bar) compared with 1 nm ghrelin (black bar); *p < 0.001. D, Peak action potential frequency measured over 10 s in the presence of ACSF before ghrelin treatment (white bar) compared with 1 nm ghrelin (black bar) in the same cells; *p < 0.05.