Skip to main content
. 2019 Jul 30;9:11055. doi: 10.1038/s41598-019-47444-6

Table 2.

Microglia immunophenotype suggests differences in immune vigilance for D-MG and MG groups.

Gene Name MG-1 MG-2 MG-3 D-MG-1 D-MG-2 D-MG-3 Ave (MG) Ave (D-MG) DMG/MG LOG2 (DMG/MG)
Interferon pathway
STAT1 18.863 18.003 17.906 12.591 16.296 13.932 18.258 14.273 0.782 −0.36
STAT4 0.321 0.448 0.235 0.242 0.177 0.259 0.335 0.226 0.675 −0.57
OAS1 0.238 0.232 0.199 0.087 0.055 0.101 0.223 0.081 0.362 −1.47
IFIT2 0.974 0.912 0.756 0.164 0.172 0.229 0.881 0.189 0.214 −2.22
PLSCR1 12.662 11.825 11.660 1.949 1.710 2.083 12.049 1.914 0.159 −2.65
IFITM3 465.310 367.927 441.155 53.291 57.131 73.014 424.797 61.145 0.144 −2.80
SIGLEC family
SIGLEC1 0.028 0.021 0.020 0.111 0.114 0.129 0.023 0.118 5.178 2.37
SIGLEC11 0.030 0.000 0.000 0.109 0.017 0.000 0.010 0.042 4.223 2.08
SIGLEC14 0.000 0.022 0.000 0.000 0.052 0.032 0.007 0.028 3.817 1.93
SIGLEC5 0.000 0.018 0.000 0.023 0.043 0.000 0.006 0.022 3.615 1.85
SIGLEC16 0.029 0.029 0.082 0.143 0.170 0.166 0.047 0.160 3.415 1.77
SIGLEC15 0.094 0.092 0.088 0.114 0.073 0.044 0.091 0.077 0.845 −0.24
SIGLEC10 0.125 0.190 0.078 0.135 0.081 0.039 0.131 0.085 0.649 −0.62
SIGLEC6 0.197 0.600 1.104 0.133 0.203 0.279 0.634 0.205 0.324 −1.63
SIGLEC9 0.023 0.046 0.033 0.028 0.000 0.000 0.034 0.009 0.279 −1.84
Activating members
TREM1 0.015 0.015 0.151 0.169 0.412 0.000 0.061 0.194 3.195 1.68
CD300LB 0.062 0.020 0.115 0.200 0.119 0.058 0.066 0.126 1.916 0.94
CD300LF 0.023 0.022 0.000 0.028 0.000 0.032 0.015 0.020 1.329 0.41
Inhibitory members
SIGLEC5 0.000 0.018 0.000 0.023 0.043 0.000 0.006 0.022 3.615 1.85
CD200 11.187 13.126 11.137 18.303 20.706 20.599 11.817 19.869 1.681 0.75
CD300A 0.974 0.829 0.908 0.728 1.012 0.529 0.904 0.756 0.837 −0.26
CD47 12.758 15.348 12.051 9.623 9.966 9.872 13.386 9.820 0.734 −0.45
CD200R1 0.296 0.231 0.221 0.072 0.160 0.056 0.249 0.096 0.385 −1.38
SIRPA 5.045 4.001 4.854 0.885 0.880 1.207 4.634 0.991 0.214 −2.23
CD22 1.090 1.023 0.902 0.157 0.083 0.121 1.005 0.120 0.120 −3.06

The FPKM (fragments per kilobase per million reads) normalized values for these genes are listed for all samples. The numbers in the last column are the Log2 values of ratios of D-MG to MG. Negative values indicate that the genes are present in higher amounts in MG group, while positive values indicate that the genes are present in higher amounts in D-MG group.