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Neuronal number is not altered in Erk2 CKO mice. A, B, Cortical coronal sections are immunostained for the neuronal marker NeuN. No significant difference is detected in the number of NeuN+ cells between controls and Erk2 CKO mice at 13 (A) and 7 (B) weeks of age. C, The fold differences in the numbers of NeuN+ cells at 13 weeks of age are calculated (CKO vs control, n = 5 mice for each, t = 0.33, t test, p > 0.05). Scale bars, 100 μm.
