Figure 1.
GABAergic action in the hippocampus. A, Left, Recording configuration. Center, A laminar profile of cFields, which were sequentially recorded by an electrode (left) positioned in multiple layers of the CA1 area. The stimulation electrode (right) was placed within the SP. Calibration: 5 ms, 100 μV. Right, CSD analysis of cFields. Asterisk, The initiation site of current source signal. SO, stratum oriens; SR, stratum radiatum; SLM, stratum lacunosum-moleculare. B, Recordings and analysis similar to those in A; the stimulation electrode (right) was placed within the GCL. Calibration: 5 ms, 50 μV. Asterisk, The initiation site of current sink signal. C, Plot of cField recorded in the CA1-SP and DG-GCL areas against postnatal ages. D, Summary of cFields recorded in the CA-SP and DG-GCL areas before and after GZ treatment. Traces, Representative cFields recorded from indicated areas. Calibration: 20 ms, 100 μV. E, Summary of τrise and τdecay of cFields recorded from the CA-SP and DG-GCL areas.