Table 2.
Definitions and values of parameters
| Corticostriatal model (Fig. 2A,B) | Schaffer-collateral model (Fig. 2C–F) | Hotspot model, and single neuron model (Figs. 5–8) | ||
|---|---|---|---|---|
| αV | VDCC coefficient | 2.0 | 2.0 | 2.0 |
| αN | NMDA voltage dependence | 1.0 | 1.0 | 1.0 |
| βN | NMDA baseline | 0.0 | 0.0 | 1.0 |
| γA | AMPA coefficient | 1.0 | 1.0 | 1.0 |
| γN | NMDA coefficient | 0.05 | 0.2 | 0.2 |
| γBP | Backpropagation coefficient | 8.0 | 8.5 | 8.0 |
| γI | Inhibitory heterosynaptic effect | 5.0 | 3.0 | 1.2 (Figs. 5–7) |
| 2.5 (Fig. 8) | ||||
| γE | Excitatory heterosynaptic effect | 0.0 | 1.0 | 0.0 |
| θp | LTP threshold | 70 | 70 | 70 |
| θd | LTD threshold | 35 | 35 | 35 |
| Cp | LTP constant | 2.3 | 2.2 | 2.11 in (Figs. 5, 7) |
| 2.01 (Fig. 6) | ||||
| 1.85 (Fig. 8) | ||||
| Cd | LTD constant | 1.0 | 1.0 | 1.0 |
| yth | Plasticity threshold | 250 | 750 | 250 (Figs. 5–7) |
| 750 (Fig. 8) |