Table 2. Participants of the UK Biobank Included in This Studya.
| Study | UK Biobankb |
|---|---|
| Participants, No. | 452 302 |
| Sex, No. (%) | |
| Men | 206 951 (46) |
| Women | 245 351 (54) |
| Age at baseline, mean (SD), y | 57 (8) |
| Men | 57 (8) |
| Women | 57 (8) |
| Currently smoking, No. (%) | 47 036 (10) |
| Men | 25 165 (12) |
| Women | 21 867 (9) |
| Body mass index, mean (SD) [No. missing]c | 27.4 (4.8) [1594] |
| Men | 27.9 (4.2) |
| Women | 27.0 (5.1) |
| Waist-to-hip ratio, mean (SD) [No. missing] | 0.87 (0.09) [883] |
| Men | 0.94 (0.07) |
| Women | 0.82 (0.07) |
| Waist circumference, mean (SD) [No. missing], cm | 90 (13.5) [790] |
| Men | 97 (11.4) |
| Women | 85 (12.5) |
| Hip circumference, mean (SD) [No. missing], cm | 103 (9.2) [838] |
| Men | 104 (7.6) |
| Women | 103 (10.3) |
| Systolic blood pressure, mean (SD) [No. missing], mm Hg | 138 (19) [863] |
| Men | 141 (17) |
| Women | 135 (19) |
| Diastolic blood pressure, mean (SD) [No. missing], mm Hg | 82 (10) [850] |
| Men | 84 (10) |
| Women | 81 (10) |
The exact numbers of participants included in each genetic analysis are in eTable 1 in the Supplement.
Genotyping in the UK Biobank was performed using the Affymetrix UK BILEVE and UK Biobank Axiom arrays, with Haplotype Reference Consortium r1.1 as the imputational panel.
Calculated as weight in kilograms divided by height in meters squared.