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LTP induction does not depend on activation of group 2 mGluRs. A, The group 2 mGluR antagonist MSOPPE (n = 7) does not inhibit LTP in the CA1 region when compared with vehicle-injected controls (n = 6).B, Original analog traces showing evoked responses in the CA1 region at three time points: preinjection,t = 5 min, and t = 4 hr post-HFT, in an animal injected with MSOPPE (40 mm/5 μl). Line breaks (//) indicate change in time scale.
