Fig. 3.
The Ca2+-exocytosis relationship during pulse trains can be depressed relative to the standard transfer function obtained from single pulse depolarizations.A, Cumulative Cm increases from three different cells, stimulated with (A,i) 5 msec duration, 30 pulses, (A,ii) 10 msec duration, 30 pulses, (A,iii) 20 msec duration, 20 pulses. The dashed curve is a plot of the standard transfer function. Cells L031105, Chr110, Chr043. B, CumulativeCm increases from three different cells stimulated with 40 msec duration, 10 pulses. Cells Chr171, Chr138, N012702. C, Percentage of cells that responded to a given stimulus protocol with a Ca2+ efficacy that was depressed relative to the standard transfer function. Same data set as Figures 1C, 2C (see legend to Fig.1).