S2.
TNM staging of esophageal carcinoma (AJCC 8th edition 2017)
| Definitions of primary tumor, regional lymph node, distant metastasis for esophageal carcinoma |
| Primary tumor (T) |
| TX Tumor cannot be assessed |
| T0 No evidence of primary tumor |
| Tis High-grade dysplasia |
| T1 Tumor invades the lamina propria, muscularis mucosae
or submucosa |
| T1a Tumor invades the lamina propria or
muscularis mucosae |
| T1b Tumor invades the submucosa |
| T2 Tumor invades the muscularis propria |
| T3 Tumor invades adventitia |
| T4 Tumor invades adjacent structures |
| T4a Tumor invades the pleura, pericardium, azygos
vein, diaphragm or peritoneum |
| T4b Tumor invades other adjacent structures, such as
the aorta, vertebral body or airway |
| Regional lymph node (N) |
| NX Regional lymph nodes cannot be assessed |
| N0 No regional lymph node metastasis |
| N1 Metastasis in one to two regional lymph nodes |
| N2 Metastasis in three to six regional lymph nodes |
| N3 Metastasis in seven or more regional lymph nodes |
| Distant metastasis (M) |
| M0 = No distant metastasis |
| M1 = Distant metastasis |