Fig. 6.
Tumor glycolytic activity is correlated with immunotherapy response. A. High glycolytic activity is associated with increased immunotherapy response rate in two melanoma cohorts (Hugo cohort [26] and Nathanson cohort [27]). B. Kaplan-Meier survival curves show that the glycolysis score and the expression of the glycolysis-associated genes are positively correlated with survival prognosis in the immunotherapeutic cohorts. C. Kaplan-Meier survival curves show that the glycolysis score is negatively correlated with survival prognosis in multiple TCGA cohorts without immunotherapy. OS: overall survival. DFS: disease-free survival. The log-rank test P values are shown in the survival curves.