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. 2019 Apr 7;12(2):78–87. doi: 10.14740/gr1156

Table 1. Associations of Arginase-1/CK19 Expression and Clinicopathologic Parameters in HCC.

Variables n Arginase-1
 CK19
High Low P value Positive Negative P value
Age 0.617 0.617
  ≥ 65 57 46 11 11 46
  < 65 55 47 8 8 47
Sex 0.16 0.779
  Male 81 70 11 13 68
  Female 31 23 8 6 25
HBV 0.022 0.103
  Present 20 20 0 6 14
  Absent 92 73 19 13 79
HCV 1 0.615
  Present 61 51 10 9 52
  Absent 51 42 9 10 41
AFP 0.217 0.083
  Low 62 54 8 7 55
  High 50 39 11 12 38
Cirrhosis 0.602 1
  Present 72 61 11 12 60
  Absent 40 32 8 7 33
Tumor size
  ≥ 5 cm 29 21 8 0.089 5 24 1
  < 5 cm 83 72 11 14 69
Tumor number 0.29 0.598
  Solitary 73 63 10 11 62
  Multiple 39 30 9 8 31
Grade 0.309 0.077
  I-II 68 54 14 8 60
  III-IV 44 39 5 11 33
Vascular invasion 0.044 0.273
  Present 30 21 9 7 23
  Absent 82 72 10 12 70
TNM stage 0.009 1
  I-II 95 83 12 16 79
  III-IV 17 10 7 3 14

HCC: hepatocellular carcinoma; n: number; HBV: hepatitis B virus; HCV: hepatitis C virus; TNM: tumor-node-metastasis; AFP: alpha-fetoprotein; CK19: cytokeratin 19.