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. 2019 Jan 15;92(3):e224–e233. doi: 10.1212/WNL.0000000000006788

Figure 4. Alzheimer pathology in the patient with primary progressive aphasia (PPA).

Figure 4

(A, B) Thioflavin-S histofluorescence in layer 5 of the supramarginal gyrus (SMG) and posterior STG of the patient with PPA. Magnification ×200. (C) Cresylviolet stain of posterior superior temporal gyrus (STG) from the autopsy of a 54-year-old neurologically intact person shows pyramidal neurons (arrows) organized in columnar fashion. Magnification ×100. (D) Cresylviolet stain from posterior STG in the patient with PPA shows gliosis, angulated pyknotic neurons, and loss of columnar architecture. Magnification ×100.