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Increase in BMD in postmenopausal women treated with alendronate or estrogen, alone or in combination. PLO, Placebo; ALN, alendronate; CE, conjugated estrogen. [Reproduced with permission from H. G. Bone et al. J Clin Endocrinol Metab 85:720–726, 2000 (75). © The Endocrine Society.]
