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. Author manuscript; available in PMC: 2019 Jun 28.
Published in final edited form as: J Med Chem. 2018 Jun 18;61(12):5412–5423. doi: 10.1021/acs.jmedchem.8b00733

Figure 3.

Figure 3.

Effects of JC124 treatment on cognitive functions in APP/PS1 mice. At the age of 7 months old, animals were randomly divided into the following experimental groups: WT mice, vehicle group (n = 4), JC124 treatment group (n = 6); Tg mice, vehicle group (n = 5), JC124 treatment group (n = 7). Starting at the age of 7 months old, animals were treated for 8 weeks (5 times/week). After completing treatment, animals were tested on cognitive functions using NOR (A) and MWM (B and C) methods.