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. Author manuscript; available in PMC: 2018 Sep 29.
Published in final edited form as: Cancer Cell. 2017 Jun 12;31(6):737–754.e6. doi: 10.1016/j.ccell.2017.05.005

Figure 6. Clinical and Genomic Characteristics of the Three Group 4 Medulloblastoma Subtypes.

Figure 6

(A) Network representation map of k = 3 SNF-derived subtypes.

(B) Age at diagnosis of group 4 subtypes at k = 3 (Kruskal-Wallis test). Boxplot center lines show data median; box limits indicate the 25th and 75th percentiles; lower and upper whiskers extend 1.5 times the interquartile range (IQR) from the 25th and 75th percentiles, respectively. Outliers are represented by individual points.

(C) Overall survival of group 4 subtypes (log rank test). + indicates censored cases.

(D) Incidence of metastatic dissemination at diagnosis across the three group 4 subtypes (chi-square test).

(E) Frequency and significance of broad cytogenetic events across the three group 4 subtypes. * indicates key statistically significant arm gain or deletion. Darker bars show significant arm-level events (q ≤ 0.1, chi-square test).

See also Figure S8 and Tables S2, S4.