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. Author manuscript; available in PMC: 2018 Sep 18.
Published in final edited form as: Cell Rep. 2017 Jun 27;19(13):2878–2880. doi: 10.1016/j.celrep.2017.06.008

Figure 2.

Figure 2.

mRNA analysis of cholangiocarcinoma identified an IDH-enriched cluster. A and B) Principal component analysis of RNA-seq expression data of 15,272 genes after exclusion of 541 normal liver genes. The heatmap in panel A shows the most strongly discriminant 973 genes (shared between the TCGA and the GSE26566 dataset) that define the 3 clusters. B) Three-dimensional PCA plot of TCGA CCA samples. C) Hierarchical clustering analysis of 40 samples from the CCA microarray dataset GSE26566, using the same 973 genes as in A. Genes in heatmaps A and C are shown in the same order.