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HMECs and estrogen receptor–positive breast cancer cells are less sensitive to LPIN1 knockdown. Analyses of cell death in MCF-7 (A), BT-474 (B), and normal HMECs (C). Left: confirmation of LPIN1 knockdown by shLPIN1-C. Middle: flow cytometry analysis. Right: statistical results of flow cytometry data in the middle. D) LPIN1 knockdown only slightly reduced proliferation in normal HMECs.
