Figure 2:
Example output of the SMART PCM app, showing a lung cancer patient with KRAS p.G12C mutation in the context of other lung cancer patients tested at VUMC. Further information is available to the user through interaction with the pie charts, all pieces of which are activated by touch. On the left, a pie chart shows the population distribution of gene mutations. In this example, it is evident that slightly more than half the patients have no mutation detected, whereas KRAS is the most commonly mutated gene. On the right, the distribution of variants of the mutated gene is shown, where it is evident that p.G12C is the most common KRAS mutation. In a case where a patient has no mutation detected, the variant pie chart is suppressed. Patient details (name, age, gender) are redacted to preserve PHI.