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. 2018 Jul 31;18:68. doi: 10.1186/s12894-018-0380-1

Table 2.

Clinical and pathological characteristics of patients with FGFR3 gene aberrations detected in surgical specimens

Patient Age Gender Primary site Pathologic stage Grade LVI FGFR3
TCC_03 64 M Bladder pT3N0 3 No FGFR3-TACC3 fusion
TCC_07 58 M Bladder pT2N0 2 No Y373C
TCC_13 47 M Bladder pT2N2 2 Yes R248C
TCC_14 61 M Bladder pT3N0 2 No G370C
TCC_19 66 M Bladder pT3N0 2 No 746_747insG (NM_000142)
TCC_41 55 M Renal pelvis pT3Nx 2 No FGFR3-TACC3 fusion
TCC_44 71 M Renal pelvis pT3Nx 3 Yes N532D
TCC_48 50 M Bladder pT4N3 3 No S249C
TCC_49 63 M Bladder pT1N2 2 Yes A797P
TCC_50 59 F Ureter pT3N1 2 No N532D
TCC_55 73 M Bladder pT2N0 2 No S675S
TCC_56 54 F Renal pelvis pT3Nx 2 No Y373C
TCC_61 78 M Ureter pT3Nx 3 No Y373C
TCC_63 55 M Ureter pT3N2 3 Yes R248C
TCC_70 66 M Bladder pT4N0 2 No N532D
TCC_71 80 M Bladder pT2N0 2 No FGFR3-TACC3 fusion

FGFR3 Fibroblast growth factor receptor 3, LVI Lymphovascular invasion