Fig. 2.
Phylogenetic trees of representative A(H1N1)pdm09 HA1 domain nucleotide sequences were constructed with the PhyML software package 3.0 [7] using GTR+I+Γ4 as determined by ModelTest [8]. GARLI v0.961 [9] was run on the best tree from PhyML for 2 million generations to optimise tree topology and branch lengths. Amino acid substitutions are marked on major nodes. Viruses are colour-coded by month of collection as follows: March-April 2011 in Blue, May 2011 in Green, June – July 2011 in Orange, August 2011 in Pink. The current vaccine strain is in Red. Genetic subgroups are labelled 1–8.
