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A numeric example of a false positive association due to population stratification.
| Population | Allele | Phenotype | Total | Association | |
|---|---|---|---|---|---|
|
| |||||
| Case | Control | ||||
| 1 | A | 270 | 30 | 300 | no |
| B | 630 | 70 | 700 | ||
| Total | 900 | 100 | 1000 | ||
|
| |||||
| 2 | A | 80 | 720 | 800 | no |
| B | 20 | 180 | 200 | ||
| Total | 100 | 900 | 1000 | ||
|
| |||||
| Pooled | A | 350 | 750 | 1100 | Yes |
| B | 650 | 250 | 900 | P < .0001 | |
| Total | 1000 | 1000 | 2000 | ||
