Table 1. Features of the three sybody libraries.
| Library | Template PDB entry/target |
Binding interface in template |
Length of CDR3 | Number of randomized residues in library |
Theoretical diversity of library |
|---|---|---|---|---|---|
| concave | 3K1K/GFP | 672 Å2 | 6 aa | 15 | 8.3 × 1017 |
| loop | 3P0G/GPCR | 901 Å2 | 12 aa | 16 | 4.3 × 1019 |
| convex | 1ZVH/Lysozyme | 533 Å2 | 16 aa | 18 | 2.8 × 1022 |