Figure 2. Effects of E/C/F/TDF Therapy on 18F-FDG-PET/CT Outcomes Among ART-Naïve HIV-infected Subjects.
Top row represents data as median (IQR). Bottom row displays individual data points before and after ART. Bilateral axillary lymph node TBR decreased significantly (P=0.01) and aortic TBR increased significantly (P=0.04 by two-way Wilcoxon signed rank test; P=0.98 for one-way test of decrease by Wilcoxon signed rank test). Ten of the 11 subjects’ lymph node TBR decreased while 8 of the 10 subjects’ aortic TBR increased after ART. Aortic TBR data on one participant could not be utilized as significant activity in the thymus caused spillover of activity into the aorta.