Figure 2. Infiltrating dendritic cells (DCs) are increased in the failing heart.
A, Representative confocal images of CD11c immunostained sections from sham and HF hearts (remote zone) and corresponding group data. The arrows indicate infiltrating CD11c+ DCs; n=5 per group. B, Representative scatter plots for Lin1− (defined in text) cardiac mononuclear cells further separated into CD11c+B220− classical DCs (cDCs) and CD11c+/lowB220+ plasmacytoid DCs (pDCs), expressed as a percentage of total live cells, together with quantitative group data for cDC and pDC populations in sham and HF hearts. N=8 per group. C, Flow cytometric quantification of CD86hi and CD86low pDCs in sham and HF hearts. N=4 to 5 per group.
