Fig. 2.

Performance of animals in the 5 C-CPT tested using standard conditions following SKF 38393 treatment and analysed using signal detection theory. Drug treatment produced a significant reduction in p[HR] (a). There was no effect of SKF 38393 on p[FA] (b), sensitivity index (c) or responsivity index (d). Data are expressed as mean ± SEM and analysed by one-way ANOVA followed by Planned Comparisons on the predicted means. *p < 0.05 relative to the vehicle (Veh) group