TABLE 2.
Adjusted ORs from multivariable models for the association of dietary patterns with high plasma sCD14 (overall N = 1198)1
| Dietary pattern quintiles | P-trend2 | Per 1-SD increase in dietary pattern score | |||||
|---|---|---|---|---|---|---|---|
| Statistical model | Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | ||
| Western dietary pattern | |||||||
| High:low sCD14 | 115:124 | 116:124 | 110:127 | 125:118 | 133:106 | ||
| Model 1 | 1 | 1.18 (0.80, 1.74) | 1.14 (0.78, 1.69) | 1.59 (1.08, 2.34) | 1.69 (1.15, 2.50) | 0.002 | 1.22 (1.07, 1.38) |
| Model 2 | 1 | 1.25 (0.85, 1.86) | 1.28 (0.86, 1.91) | 1.69 (1.14, 2.52) | 1.86 (1.24, 2.79) | 0.0006 | 1.26 (1.10, 1.44) |
| Prudent dietary pattern | |||||||
| High:low sCD14 | 114:125 | 119:121 | 121:119 | 131:109 | 114:125 | ||
| Model 1 | 1 | 0.85 (0.57, 1.26) | 0.95 (0.64, 1.40) | 1.11 (0.75, 1.64) | 0.79 (0.54, 1.17) | 0.46 | 0.95 (0.84, 1.08) |
| Model 2 | 1 | 0.82 (0.55, 1.22) | 0.92 (0.62, 1.38) | 1.09 (0.73, 1.62) | 0.73 (0.49, 1.09) | 0.30 | 0.94 (0.82, 1.06) |
Values are n or ORs (95% CIs) modeling the probability of high sCD14 concentrations (i.e., greater than or equal to the median of 1915 ng/mL) unless stated otherwise. sCD14 concentrations were natural log transformed prior to analyses. Dietary patterns were adjusted for energy using the residual methods. Model 1 was adjusted for age at blood draw and sex. Model 2 was additionally adjusted for physical activity, smoking status, case-control status, BMI (in kg/m2), chronic disease comorbidity score, and regular use of aspirin, acetaminophen, other nonsteroidal anti-inflammatory drugs, or cholesterol-lowering drugs. Chronic diseases or conditions included in the score were hypercholesterolemia, cancer, diabetes, high blood pressure, heart disease, rheumatoid or other arthritis, or Crohn disease or ulcerative colitis. sCD14, soluble CD14.
The P value for linear trend was the P value for the dietary pattern as a continuous variable adjusted for all covariates listed in footnote 1.