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. 2017 Oct 24;114(45):11832–11837. doi: 10.1073/pnas.1712350114

Fig. 2.

Fig. 2.

DGC overview. (A) Summary of control equation variables. (B) Each TAD is a node in a dynamic network. The blue connections represent the edges of the network and are determined from time series fibroblast RNA-seq data. The green plots represent the expression of each TAD changing over time. The red arrows indicate additional regulation imposed by exogenous TFs. (C) A conceptual illustration of the problem: Can we determine TFs to push the cell state from one basin to another?