Skip to main content
. 2017 Nov 7;7:14761. doi: 10.1038/s41598-017-15348-y

Figure 2.

Figure 2

The acquisition of the 5-HT-dependent gene signature of human M-MØ is mediated by the 5-HT7R receptor. (A) Relative expression of the indicated genes in non-treated (-) or 5-HT-treated (5HT, 6 h) M-MØ and either in the absence (-) or in the presence of the 5-HT7R antagonists SB269970 or SB258719. Results are expressed as the mRNA level of each gene relative to the TBP mRNA level in the same sample (n = 6; *p < 0.05; **p < 0.01; ***p < 0.001). (B) Relative expression of the indicated genes in M-MØ either non-treated (-) or treated for 6 h with 5-HT or the 5-HT7R agonist AS19. Results are expressed as the mRNA level of each gene relative to the TBP mRNA level in the same sample (n = 6; *p < 0.05).