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. 2017 Oct 21;174(Suppl Suppl 1):S272–S359. doi: 10.1111/bph.13877
Nomenclature mechanistic target of rapamycin
HGNC, UniProt MTOR, P42345
EC number 2.7.11.1
Common abreviation mTOR
Inhibitors ridaforolimus (pIC50 9.7) [441], torin 1 (pIC50 9.5) [310], INK‐128 (pIC50 9) [231], INK‐128 (pK i 8.9) [231], gedatolisib (pIC50 8.8) [544], dactolisib (pIC50 8.2) [332], PP‐242 (pIC50 8.1) [15], PP121 (pIC50 8) [15], XL388 (pIC50 8) [511], PF‐04691502 (pK i 7.8) [309], apitolisib (pK i 7.8) [506]
Selective inhibitors everolimus (pIC50 8.7) [464], temsirolimus (pIC50 5.8) [278]