Fig. 6.
Representative SEM images of mouse bladders, implants, and human catheters. Tissues, implants, and catheters were processed following implantation, implantation and infection (mouse), or dwell time (human). (A–C) Mouse bladders, with each pair showing low-, medium-, and (C) high-magnification images as indicated. (Scale bars: 200, 100, and 2 μm, respectively.) (D and E) Implants, with each pair showing medium- and high-magnification images, as indicated. (Scale bars: 100 and 10 μm, respectively.) Three mice were used per group. (F) Human catheters, with each pair showing two representative images from catheters recovered from the patients analyzed in Fig. 5. [Scale bars: 2 and 10 μm (Far Right).] Labeled are the epithelium (ep); epithelial cell damage from the implant (cd); MRSA (SA); immune cell infiltrates, likely neutrophils (N); and proteins, likely fibrinogen (fg).