Figure 1.
[Na+]i dynamics in multiple compartments of the AOB mitral cell, layer V pyramidal cell, and cerebellar Purkinje cell models following a spike train. (A) The morphology of the three model cells used: AOB mitral cell with reduced geometry (blue), cortical layer V pyramidal cell (green), and cerebellar Purkinje cell (red). (B) [Na+]i dynamics in the AIS of the mitral cell model (blue), pyramidal cell model (green), and Purkinje cell model (red) during and after a 30 Hz spike train (red bar). The inset shows the spike shape in the three model cells. (C–E) Similar comparison of [Na+]i dynamics in the cell somata, proximal dendrite, and distal dendrite. (F) [Na+]i dynamics in the third node of Ranvier of the Purkinje cell model.