Table 1.
Patients characteristics
| Variable | Category | Patients (n=137) | |
|---|---|---|---|
| n | % | ||
|
| |||
| Center | Amsterdam | 44 | 32 |
|
| |||
| Essen | 11 | 8 | |
|
| |||
| Lausanne | 10 | 7 | |
|
| |||
| Nantes | 6 | 4 | |
|
| |||
| Naples | 18 | 13 | |
|
| |||
| New York | 40 | 29 | |
|
| |||
| Siena | 8 | 58 | |
|
| |||
| Gender | Male | 76 | 55 |
|
| |||
| Female | 61 | 45 | |
|
| |||
| Age | ≤ 40 years | 19 | 14 |
|
| |||
| > 40 years | 57 | 42 | |
|
| |||
| > 60 years | 31 | 23 | |
|
| |||
| > 70 years | 30 | 22 | |
|
| |||
| Median age | 58 years | ||
|
| |||
| Number of doses | 1 | 7 | 5 |
|
| |||
| 2 | 8 | 6 | |
|
| |||
| 3 | 18 | 13 | |
|
| |||
| 4 | 104 | 76 | |
|
| |||
| M category (AJJC) | M1a | 13 | 10 |
|
| |||
| M1b | 25 | 18 | |
|
| |||
| M1c | 98 | 72 | |
|
| |||
| Unknown | 1 | n.c. | |
|
| |||
| Treatment background | CA-184–169 (3 or 10 mg/kg) | 3 | 2 |
|
| |||
| Early access program (3 mg/kg) | 68 | 50 | |
|
| |||
| Regular prescription (3 mg/kg) | 66 | 48 | |
|
| |||
| Best clinical response (irRC) | Complete /partial response | 34 | 26 |
|
| |||
| Stable /progressive disease | 96 | 74 | |
|
| |||
| Unknown | 7 | n.c. | |