Table 4.
Correlation between central and invasive area for estimates of area fraction
| Spearman correlation All sections (n = 129) |
Spearman correlation Deepest section (n = 43) | Spearman correlation Random section A (n = 43) |
Spearman correlation Random section B (n = 43) |
|
|---|---|---|---|---|
| CD3-Central | 0.9404 | 0.9434 | 0.9322 | 0.9244 |
| CD8-Central | 0.9603 | 0.9499 | 0.9671 | 0.9269 |
| CD3-Invasive | 0.9400 | 0.9406 | 0.9394 | 0.9710 |
| CD8-Invasive | 0.9497 | 0.9665 | 0.9080 | 0.9557 |
Correlation between area fractions of CD3+ and CD8+ tumor infiltrating lymphocytes in central and invasive tumor areas, respectively, estimated by either stereology or image analysis for all tumor sections and for individual tumor sections
Spearman’s correlation, p < 0.0001