Table 3.
Features of sepsis for all encounters.
| Variable | Overall (n = 3917) | Before (n = 1929, 49%) | After (n = 1988, 51%) | p-Value |
|---|---|---|---|---|
| Systolic blood pressure (mm Hg) | 123.6 (30.5); n = 3013 | 122.9 (30.9); n = 1472 | 124.3 (30.1); n = 1541 | 0.23a |
| Initial HR (beats/min) | 101.3 (23.6); n = 3663 | 100.3 (24.0); n = 1775 | 102.18 (23.2); n = 1888 | 0.009a |
| Initial RR (breaths/min) | 19.7 (5.1); n = 3742 | 19.6 (5.3); n = 1833 | 19.75 (5.31); n = 1909 | 0.05a |
| Initial temperature (°F) | 98.8 (2.1); n = 3749 | 100.3 (24.0); n = 1833 | 98.9 (2.3); n = 1916 | 0.0007a |
| Oxygen saturation (%) | 93.4 (7.0); n = 1010 | 93.4 (7.4); n = 515 | 93.5(6.7); n = 495 | 0.42a |
| Initial WBC (thous/mm3) | 13.6 (8.1); n = 3786 | 13.6 (8.0); n = 1857 | 13.2 (8.2); n = 1929 | 0.85a |
| Lactate (mmol/L) | 2.7 (2.8); n = 1967 | 3.0 (3.0); n = 968 | 2.6 (2.6); n = 999 | 0.05a |
| Lactatec n (%) | ||||
| ≥4 mmol/L | 315 (16) | 170 (18) | 145 (15) | 0.07b |
| <4 mmol/L | 1652 (84) | 798 (82) | 854 (85) | |
| Creatinine mg/dL | 1.8 (2.3); n = 3842 | 1.9 (2.3); n = 1872 | 1.78 (2.3); n = 1970 | 0.15a |
| Positive culture, n (%) | 0.34b | |||
| Blood | 1284 (35) | 700 (35) | 584 (35) | |
| Respiratory | 1093 (30) | 573 (29) | 520 (31) | |
| Urine | 1088 (30) | 606 (31) | 482 (29) | |
| Wound | 201 (5) | 102 (5) | 99 (5) | |
| Total | 3666 (100) | 1981 (54) | 1685 (46) | |
a
Wilcoxon rank-sum test.
b
Pearson’s Chi-square test.
c
Lactate at first admission.