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. 2017 Apr 15;8(26):42438–42454. doi: 10.18632/oncotarget.17124

Figure 4. VPC-18005 inhibits SOX9 gene expression.

Figure 4

(A) SOX9 and ERG mRNA levels in VCaP cells treated with and without 1 nM R1881 and 25 μM VPC-18005. ***p < 0.001; *p < 0.05, Kruskal–Wallis test with Dunn's multiple comparison post-hoc test. (B) SOX9 and ERG mRNA levels in VCaP cells transfected with ERG siRNA for 48 h. *p < 0.0001, unpaired t-test; # p = 0.0007, Mann-Whitney-U test. Expression of ERG and SOX9 was normalized to GAPDH. Data points represent experiment performed in triplicate. Error bars indicate standard error of mean for n = 9 values.