Table 3.
Results from sigmoidal modeling on global cognition
| Parameters | Estimate | Standard Error | Pr > |t| |
|---|---|---|---|
| Initial level | |||
| α4 | 0.587 | 0.057 | <.0001 |
| Education | 0.018 | 0.009 | 0.045 |
| Age at baseline | −0.016 | 0.005 | 0.000 |
| BMI at baseline | 0.002 | 0.005 | 0.725 |
| Decline midpoint | |||
| α 2 | −1.402 | 0.172 | <.0001 |
| Education | 0.001 | 0.027 | 0.981 |
| Age at baseline | 0.169 | 0.029 | <.0001 |
| Age at death | −0.216 | 0.025 | <.0001 |
| Range of BMI | −0.265 | 0.048 | <.0001 |
| Rate of decline | |||
| α 3 | 0.830 | 0.091 | <.0001 |
| Education | 0.027 | 0.009 | 0.003 |
| Age at baseline | −0.033 | 0.009 | 0.001 |
| Age at death | 0.067 | 0.010 | <.0001 |
| Range of BMI | 0.037 | 0.014 | 0.009 |
| Level at death | |||
| α 1 | −0.902 | 0.092 | <.0001 |
| Education | 0.016 | 0.022 | 0.465 |
| Age at death | −0.037 | 0.012 | 0.003 |
| Last BMI before death | −0.016 | 0.014 | 0.237 |
| Variance and covariance | |||
| Error | 0.246 | 0.003 | <.0001 |
| u | 2.120 | 0.227 | <.0001 |
| v | 0.174 | 0.034 | <.0001 |
| u,v | −0.284 | 0.100 | 0.005 |
Education represents years of formal education centered at 17 years. Age at baseline and at death is centered respectively at 79 and 89 years. BMI at baseline and the last before death were centered at 26.