Table 2.
Age distribution, covariate and clinical characteristics for the 9,114 women included in analysis, according to smoking status at diagnosis
| Smoking status
|
||||||
|---|---|---|---|---|---|---|
| Characteristics | Never N (%) | Former N (%) | Current N (%) | |||
| Number of Women | 4,966 (54.5) | 2,900 (31.8) | 1,248 (13.7) | |||
|
| ||||||
| Age at diagnosis (years)1 | ||||||
|
| ||||||
| <40 | 328 | (6.6) | 114 | (3.9) | 119 | (9.5) |
|
| ||||||
| 40–49 | 953 | (19.2) | 463 | (16.0) | 326 | (26.1) |
|
| ||||||
| 50–59 | 1,528 | (30.8) | 965 | (33.3) | 408 | (32.7) |
|
| ||||||
| 60–69 | 1,356 | (27.3) | 913 | (31.5) | 279 | (22.4) |
|
| ||||||
| ≥70 | 801 | (16.1) | 445 | (15.3) | 116 | (9.3) |
|
| ||||||
| Tumor stage1 | ||||||
|
| ||||||
| Localized | 952 | (19.2) | 529 | (18.2) | 284 | (22.8) |
|
| ||||||
| Regional | 1,158 | (23.3) | 647 | (22.3) | 231 | (18.5) |
|
| ||||||
| Distant | 2,856 | (57.5) | 1,724 | (59,4) | 733 | (58.7) |
|
| ||||||
| Histology1 | ||||||
|
| ||||||
| Serous | 2,899 | (58.3) | 1,829 | (63.1) | 727 | (58.3) |
|
| ||||||
| Serous low-grade | 218 | (4.4) | 142 | (4.9) | 81 | (6.5) |
|
| ||||||
| Serous high-grade | 2,681 | (54.0) | 1,687 | (58.2) | 646 | (51.8) |
|
| ||||||
| Mucinous | 316 | (6.4) | 161 | (5.6) | 134 | (10.7) |
|
| ||||||
| Endometrioid | 839 | (16.9) | 460 | (15.9) | 174 | (13.9) |
|
| ||||||
| Clear cell | 374 | (7.5) | 150 | (5.2) | 76 | (6.1) |
|
| ||||||
| Other | 538 | (10.8) | 300 | (10.3) | 137 | (11.0) |
|
| ||||||
| Grade1 | ||||||
|
| ||||||
| Well differentiated | 634 | (12.8) | 357 | (12.3) | 214 | (17.1) |
|
| ||||||
| Moderately differentiated | 1,286 | (25.9) | 709 | (24.4) | 317 | (25.4) |
|
| ||||||
| Poorly differentiated | 2,739 | (55.2) | 1,657 | (57.1) | 669 | (53.6) |
|
| ||||||
| Undifferentiated | 307 | (6.2) | 177 | (6.1) | 48 | (3.8) |
|
| ||||||
| Race/ethnicity1 | ||||||
|
| ||||||
| Non-Hispanic White | 4,187 | (84.3) | 2,629 | (90.7) | 1,108 | (88.8) |
|
| ||||||
| Hispanic White | 150 | (3.0) | 73 | (2.5) | 25 | (2.0) |
|
| ||||||
| Black | 103 | (2.1) | 71 | (2.4) | 60 | (4.8) |
|
| ||||||
| Asian | 369 | (7.4) | 59 | (2.0) | 18 | (1.4) |
|
| ||||||
| Other | 156 | (3.1) | 67 | (2.3) | 34 | (2.7) |
|
| ||||||
| BMI | ||||||
|
| ||||||
| Median | 24.19 | 24.33 | 23.43 | |||
|
| ||||||
| Interquartile range | 21.48–28. | 34 | 21.64–28.59 | 20.90–27.48 | ||
|
| ||||||
| Missing | 359 | (7.2) | 217 | (7.5) | 52 | (4.2) |
|
| ||||||
| Level of education | ||||||
|
| ||||||
| ≤high school | 2,168 | (43.7) | 1,275 | (44.0) | 771 | (61.8) |
|
| ||||||
| >high school | 2,621 | (52.7) | 1,516 | (52.3) | 438 | (35.1) |
|
| ||||||
| Missing | 177 | (3.6) | 109 | (3.7) | 39 | (3.1) |
|
| ||||||
| Residual disease2 | ||||||
|
| ||||||
| No macroscopic disease present | 539 | (10.9) | 255 | (8.8) | 128 | (10.3) |
|
| ||||||
| Macroscopic disease present | 714 | (14.4) | 420 | (14.5) | 214 | (17.1) |
|
| ||||||
| Missing | 3,713 | (74.8) | 2,225 | (76.7) | 906 | (72.6) |
1
No missing data.
2
Only seven studies provided information on residual disease (AUS, HAW, JPN, MAL, MAY, NCO and NEC).