Table 3.
Multivariate linear regression analysis of risk factors for CHD and stroke as estimated using the UKPDS risk engine.
| Variables | UKPDS CVD risk | UKPDS stroke risk | UKPDS fatal CVD risk | UKPDS fatal stroke risk | ||||
|---|---|---|---|---|---|---|---|---|
| Beta | P | Beta | P | Beta | P | Beta | P | |
| Male | −0.355 | 0.000 | −0.168 | 0.000 | −0.304 | 0.000 | −0.142 | 0.000 |
| Age | 0.726 | 0.000 | 0.602 | 0.000 | 0.711 | 0.000 | 0.507 | 0.000 |
| BMI | −0.023 | 0.040 | 0.004 | NS | −0.023 | NS | −0.004 | NS |
| Duration | 0.081 | 0.000 | 0.270 | 0.000 | 0.148 | 0.000 | 0.248 | 0.000 |
| SBP | 0.082 | 0.000 | 0.044 | NS | 0.101 | 0.000 | 0.232 | 0.000 |
| DBP | −0.020 | NS | 0.000 | NS | −0.025 | NS | −0.022 | NS |
| HbA1c | 0.352 | 0.000 | 0.031 | NS | 0.363 | 0.000 | 0.041 | 0.025 |
| LDL−c | −0.024 | NS | −0.022 | NS | −0.016 | NS | −0.022 | NS |
| HDL−c | −0.285 | 0.000 | −0.045 | 0.050 | −0.233 | 0.000 | −0.043 | NS |
| TC | 0.302 | 0.000 | 0.061 | NS | 0.237 | 0.000 | 0.050 | NS |
| TG | 0.000 | NS | 0.032 | NS | −0.004 | NS | 0.024 | NS |
| Smoking | 0.051 | 0.000 | 0.019 | NS | 0.014 | NS | 0.018 | NS |
| PAD | 0.055 | 0.000 | 0.140 | 0.000 | 0.066 | 0.019 | 0.140 | 0.000 |
NS: not significant; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL-c: high-density lipoprotein cholesterol; LDL-c: low-density lipoprotein cholesterol; PAD: peripheral arterial disease; ABI: ankle-brachial index; TG: triglyceride; TC: total cholesterol; HbA1c: glycosylated hemoglobin; UKPDS: United Kingdom Prospective Diabetes Study; CHD: coronary heart disease.