Fig. 4. Subtelomere size plasticity and structural rearrangements.
(a) Size variation of the 32 orthologous subtelomeres across the 12 strains. (b) Dotplot for the chr15-R subtelomere comparison between S. cerevisiae DBVPG6765 and S288C. The extended DBVPG6765 chr15-R subtelomere is explained by a previously reported eukaryote-to-eukaryote horizontal gene transfer (HGT) event. (c) Dotplot for the chr07-R subtelomere comparison between S. paradoxus CBS432 and N44. The chr07-R subtelomere expansion in CBS432 is explained by a series of tandem duplications of the MAL31-like and MAL33-like genes and an addition of the ARR-containing segment from the ancestral chr16-R subtelomere. (d) Dotplot for the chr15-L subtelomere comparison between S. paradoxus UFRJ50816 and YPS138. The expanded chr15-L subtelomere in UFRJ50816 is explained by the relocated subtelomeric segments from the ancestral chr10-L and chr03-R subtelomeres. Please note that the region coordinates in panel (b)-(d) are based on the defined subtelomeres rather than the full chromosomes.
