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. 2017 Mar 17;8(18):30276–30287. doi: 10.18632/oncotarget.16326

Table 1. The relationship between PD-L1 expression and clinicopathological features of osteosarcoma.

Clinic pathological features No. of cases (%) PD-L1 expression High (%) PD-L1 expression Low (%) P value
All patients 72 (100)
Age, y ≤ 18 32 (52.2) 15 (51.4) 17 (48.6) 0.4763
> 18 40 (47.8) 15 (31.3) 25(68.7)
Gender Male 43 (62.1) 17 (40.0) 26 (60.0) 0.8079
Female 29 (37.9) 13 (44.4) 16 (55.6)
Metastasis Absent 24 (32.8) 2 (40.9) 22 (59.1) < 0.0001
Present 48 (67.2) 28 (42.2) 20 (57.8)
Recurrence Absent 49 (70.1) 19 (42.6) 30 (57.4) 0.6089
Present 23 (29.9) 11 (40.0) 12 (60.0)
Response to preoperative chemotherapy Good* 10 (12.1) 3 (62.5) 7 (37.5) 0.1642
Poor 40 (54.6) 23 (41.7) 17 (58.3)
N/A 22 (33.3) 4 (59.1) 18 (40.9)
PD-L1 expression High 30 (41.8)
Low 42 (58.2)

* Necrosis over 90%.